Similac Sensitive vs Enfamil Gentlease

Similac Sensitive vs Enfamil Gentlease: Differences [What’s Better?]

Similac Sensitive vs Enfamil Gentlease: what are the main differences and which one is better for your baby? The short answer is that if your baby has a gassy and fussy stomach and is sensitive to lactose go for Similac Sensitive. But if your newborn cries a lot due to discomfort caused by gas and is intolerant to proteins Enfamil Gentlease is the better option. Keep reading to see how these two compare in nutrients, price, and ingredients.

Similac Sensitive
  • Some babies find it difficult to digest the proteins there
  • High sugar content
  • Contains a high amount of corn syrup
  • Available in different sizes
  • Comes in both powder & ready to feed liquid form
  • For infants who have a fussy and gassy stomach because of lactose intolerance
  • Better taste compared to Enfamil Gentlease
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Enfamil Gentlease
  • For babies who need simpler proteins
  • More gentle on the stomach
  • Relatively low sugar content
  • Reduces the child’s gas and fussiness in 24 h
  • Available in powder & ready to feed liquid
  • Available in different sizes
  • Contains all the ingredients a baby requires for healthy growth
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Similac Sensitive Review


  • If your baby has a gassy and fussy stomach due to his/her intolerance to lactose, this is the  product for your little one
  • It is a non-GMO product and doesn’t consist any artificial growth hormones
  • Consists of Human Milk Oligosaccharides (HMOs) and OptiGro (Vitamin E, DHA, etc.,) the important nutrients found in breast milk
  • Helps in the development of the brain and eyes of infants
  • Also available in ready to feed liquid
  • Contains all the important ingredients required for the overall health of babies


  • Might be difficult to digest for some newborns
  •  Not for children who have galactosemia


Similac Sensitive treats gassy and fussy stomachs of babies who are sensitive to lactose by using milk protein isolates.

It consists of some of the most essential nutrients required for the healthy growth and development of infants. These nutrients include Vitamin E, Lutein, DHA and Iron, etc. all of which are found in breast milk as well.

Another important ingredient it contains is Human Milk Oligosaccharides (HMOs) which boosts the immune system of babies.

But with all of these important ingredients, this product also has a significant amount of sugar content which can cause health problems such as diabetes, obesity and heart diseases, etc. 

Although Similac Sensitive uses isolates proteins to make it easy for babies to digest the milk, some infants who need simpler and more broken down proteins still find it difficult to digest.

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Enfamil Gentlease Review


  • This product is perfect if your baby finds it difficult to digest high sugar content
  •   It is gentler on the stomach as it uses partially hydrolyzed and whey proteins
  • Consist of DHA and Choline both of which help in the development of the brain
  • Has a higher amount of Vitamin D which makes the bones stronger
  • It is designed to reduce the fussiness in 24 hours
  • Non-GMO version is available as well
  • Contains all the ingredients a baby needs for healthy growth


  •  It contains lactose so if your baby is sensitive to lactose he/she will have difficulty in digesting this product
  •  It has a metallic taste and some babies don’t like it at all
  •  Doesn’t contain any ingredients which specifically improves the immune system


Enfamil Gentlease uses partially hydrolyzed proteins to reduce the fussiness and gas in babies, which means the proteins are broken into very small pieces so that babies can digest the milk easily.

What’s even better is that it is proven to treat the gassy and fussy stomach in just 24 hours.

This product is made up of Non-Genetically Engineered (Non-GMO) ingredients which makes it safe because it is still unclear whether GMO products are harmful or not.

The Choline and DHA present in this formula greatly help in brain’s development while a higher amount of Vitamin D helps in making the bones of infants stronger.

However, it also contains broken down lactose so if your baby is diagnosed as fully intolerant to lactose this product isn’t for him/her.

Also, Enfamil Gentlease doesn’t contain any special ingredients to boost the immune system as Similac sensitive does.

Another issue with this product is that it doesn’t taste as good rather it has a bitter/metallic taste which actually makes it difficult to feed to some babies.

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Similac Sensitive vs Enfamil Gentlease: Differences


Sometimes, Similac Sensitive has somewhat tin like the smell as it comes in a tin, hence some babies may dislike it.

Enfamil Gentlease neither has a pleasant smell nor a bad one so it doesn’t attract or bother babies specifically because of its smell.


Similac Sensitive has a good taste and it is reported to have been liked by many babies.

Enfamil Gentlease, on the other hand, has low sugar content so it tastes a bit bitter/metallic and some moms have complained that their babies don’t drink this formula at all. 

Effects on Tummy

Similac Sensitive is made up of protein isolates and is completely lactose-free, so if your little one is intolerant to proteins and needs more broken down proteins this product might not work for him/her.

However, if that is not the case rather your baby is sensitive to lactose this product works like a charm.

Whereas, Enfamil Gentlease has proteins that are broken into very small pieces so that babies’ stomach won’t have to do this work and so it is gentler on the stomach.

However, this formula also contains small pieces of lactose which means if your baby is sensitive to lactose this product can cause problems. But since not many newborns are intolerant to lactose this product works for most of the infants.


Similac Sensitive consists of several healthy nutrients found in break milk such as Vitamin E, DHA, Leutin, which contribute to healthy growth and development of newborns.

In addition to these, it also has Human Milk Oligosaccharides (HMOs) which improves the immune system.

But it also as a high amount of sugar content, extended intake of which can cause diabetes, obesity, and cancer.

Although Enfamil Gentlease doesn’t have any ingredients that specifically help in boosting the immune system, it consists of many nutrients essential for the overall health of babies.

It also contains DHA and Choline which helps in the development of the baby’s brain and more amount of Vitamin D which helps in improving the bones. What’s more, it has relatively low sugar content.


Similac Sensitive and Enfamil Gentlease both come in powder as well as ready to feed liquids so if you don’t feel like making the perfect powder formula you can use the ready to feed version of any of the products.

Also, both of these products are available in different sizes so that you can buy the one which best suits your needs.


Enfamil Gentlease tends to be cheaper than Similac Sensitive.

However, the price is not the main deciding factor in choosing which formula you should give to your baby because as mentioned earlier it actually depends on what your baby requires.


Similac Sensitive vs Enfamil Gentlease: And the Winner Is…

The winner here is Enfamil Gentlease. Not only does it have broken down proteins which make it easy to digest the formula but it also has many essential ingredients a baby needs.

Although one can argue it doesn’t contain any specific ingredients for boosting the immune system, Enfamil Gentlease still has a lot of important ingredients that contribute to the healthy growth of a baby.

For example; DHA and Choline help in the development of the baby’s brain.

The low sugar content of Enfamil Gentlease also makes it a real winner since the extended use of high sugar content can result in serious health problems. Not to mention, Enfamil Gentlease is affordable and has a lower price than Similac Sensitive.

Whereas Similac Sensitive also brims with essential ingredients present in breast milk but the amount of sugar content and a bit difficult to digest protein isolates don’t make it a top choice for all the babies.

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